発表論文(2002年以降)
Murakami S, Terasaki K, Ramirez SI, Morrill JC, Makino S. Development of a novel, single-cycle replicable Rift Valley fever vaccine.
PLoS Negl Trop Dis. 2014 (in press)
Yamayoshi S, Yamada S, Fukuyama S, Murakami S, Zhao D, Uraki R, Watanabe T, Tomita Y, Macken C, Neumann G, Kawaoka Y. Virulence-affecting amino acid changes in the PA protein of H7N9 Influenza A viruses.
J Virol. 2014 (in press) Mohamed YM, Bangphoomi N, Yamane D, Suda Y, Kato K, Horimoto T, Akashi H. Physical interaction between bovine viral diarrhea virus nonstructural protein 4A and adenosine deaminase acting on RNA (ADAR).
Arch Virol. 2014 (in press) Sugi T, Kobayashi K, Takemae H, Gong H, Ishiwa A, Murakoshi F, Recuenco FC, Iwanaga T, Horimoto T, Akashi H, Kato K. Identification of mutations in TgMAPK1 of Toxoplasma gondii conferring resistance to 1NM-PP1. International J Parasit. 2014 (in press) Gong H, Kobayashi K, Sugi T, Takemae H, Ishiwa A,
Recuenco FC, Murakoshi F, Xuan X, Horimoto T, Akashi H, Kato K. Characterization
and binding analysis of a microneme adhesive repeat domain-containing protein
from Toxoplasma gondii. Parasitol Int. 2014 63(2):381-8. Horimoto T, Gen F, Murakami S, Iwatsuki-Horimoto K, Kato K, Akashi H, Hisasue M, Sakaguchi M, Kawaoka Y, Maeda K. Serological evidence of infection of dogs with human influenza viruses in Japan.
Vet Rec.
2014 174(4):96. Watanabe T, Kiso M, Fukuyama S, Nakajima N, Imai M,
Yamada S, Murakami S, Yamayoshi S, Iwatsuki-Horimoto K, Sakoda Y, Takashita E,
McBride R, Noda T, Hatta M, Imai H, Zhao D, Kishida N, Shirakura M, de Vries RP,
Shichinohe S, Okamatsu M, Tamura T, Tomita Y, Fujimoto N, Goto K, Katsura H,
Kawakami E, Ishikawa I, Watanabe S, Ito M, Sakai-Tagawa Y, Sugita Y, Uraki R,
Yamaji R, Eisfeld AJ, Zhong G, Fan S, Ping J, Maher EA, Hanson A, Uchida Y,
Saito T, Ozawa M, Neumann G, Kida H, Odagiri T, Paulson JC, Hasegawa H, Tashiro
M, Kawaoka Y.,Characterization of H7N9 influenza A viruses isolated from
humans.Nature. 2013 26;501(7468):551-5. Takemae H, Sugi T, Kobayashi K, Gong H, Ishiwa A, Recuenco FC, Murakoshi F, Iwanaga T, Inomata A, Horimoto T, Akashi H, Kato K: Characterization of the interaction between Toxoplasma gondii rhoptry neck protein 4 and host cellular β-tubulin. Sci Rep 3:3199, 2013.Ishiwa A, Kobayashi K, Takemae H, Sugi T, Gong H, Recuenco FC, Murakoshi F, Inomata A, Horimoto T, Kato K. Effects of dextran sulfates on the acute infection and growth stages of Toxoplasma gondii.
Parasitol Res.
2013 112: 4169-4176, . Takemae H, Sugi T, Kobayashi K, Gong H, Ishiwa A, Recuenco FC, Murakoshi F, Iwanaga T, Inomata A, Horimoto T, Akashi H, Kato K. Toxoplasma gondii RON4 binds to heparan sulfate of host cell surface.
Sci Rep.
2013 3: 3199. Kobayashi K, Takano R, Takemae H, Sugi T, Ishiwa R, Gong H, Recuenco FC, Iwanaga T, Horimoto T, Akashi H, Kato K. Analyses of interactions between heparin and the apical surface proteins of Plasmodium falciparum.
Sci Rep.
2013 3: 3178. Gong H, Kobayashi K, Sugi T, Takemae H, Ishiwa A,
Recuenco FC, Murakoshi F, Xuan X, Horimoto T, Akashi H, Kato K: Characterization
and binding analysis of a microneme adhesive repeat domain-containing protein
from Toxoplasma gondii. Parasitol Int. 2013 63(3):381-388. Ozawa, M., Shimojima M, Goto H, Watanabe S, Hatta Y, Kiso M, Furuta Y, Horimoto T, Peters NR, Hoffmann MF, Kawaoka Y: A cell-based high-throughput screening system for influenza A viral RNA transcription/replication inhibitors.
Sci Rep.
2013 3:1106. Gen F, Yamada S, Kato K, Akashi H, Kawaoka Y, Horimoto T: Attenuation of an influenza A virus due to alteration of its hemagglutinin-neuraminidase functional balance in mice.
Arch Virol.
2013 158(5):1003-1011. Murakoshi F, Horimoto T, Kato K. Molecular characterization of Cryptosporidium isolates from calves in Ishikari District, Hokkaido, Japan.
J Vet Med Sci.
2013 75(7):837-840. Iwanaga T, Sugi T, Kobayashi K, Takemae H, Gong H, Ishiwa A, Murakoshi F, Recuenco FC, Horimoto T, Akashi H, Kato K. Characterization of Plasmodium falciparum cdc2-related kinase and the effects of a CDK inhibitor on the parasites in erythrocytic schizogony.
Parasit International.
2013 62(5):423-430. Murakami S, Terasaki K, Narayanan K, Makino S. Roles of the coding and noncoding regions of Rift Valley fever virus RNA genome segments in viral RNA packaging.
J Virol. 2012 86(7):4034-9. Yamada S, Shinya K, Takada A, Ito T, Susuki T, Suzuki Y, Le QM, Ebina M, Kasai N, Kida H, Horimoto T, Rivailler P, Chen LM, Donis R, Kawaoka Y: Adaptation of a duck influenza A virus in quail.
J Virol. 2012 86(3):1411-1420. Gong H, Kobayashi K, Sugi T, Takemae H, Kurokawa H,
Horimoto T, Akashi H, Kato K: A novel PAN/apple domain- containing protein from
Toxoplasma gondii: characterization and receptor identification. PLoS ONE. 2012
7(1):e30169. Kobayashi K, Takemae H, Sugi T, Gong H, Recuenco FC,
Iwanaga T, Horimoto T, Akashi H, Kato K. Approach for the development of
antiprotozoal agents and vaccines on the basis of invasion inhibitory effect of
heparin. Jpn J Vet Parasitol. 2012 11(1): 23. Tsuda S, Watanabe S, Masangkay JS, Mizutani T, Alviola P,
Ueda N, Iha K, Taniguchi S, Fujii H, Kato K, Horimoto T, Kyuwa S, Yoshikawa Y,
Akashi H. Genomic and serological detection of bat coronavirus from bats in the
Philippines. Arch Virol. 2012 157(12): 2349-2355. Katsura H, Iwatsuki-Horimoto K, Fukuyama S, Watanabe S, Sakabe S, Hatta Y, Murakami S, Shimojima M, Horimoto T, Kawaoka Y: A replication-incompetent virus possessing an uncleavable hemagglutinin as an influenza vaccine.
Vaccine.
2012 30(42): 6027-6033. Suda Y, Yamane D, Zahoor MA, Kato K, Horimoto T, Akashi
H. Subcellular formation and localization of bovine viral diarrhea virus
replication complex. Jpn J Vet Res. 2012 60 (suppl.): 78. Murakami S, Horimoto T, Ito M, Takano R, Katsura H, Shimojima M, Kawaoka Y. Enhanced growth of influenza vaccine seed viruses in Vero cells mediated by broadening the optimal pH range for virus membrane fusion.
J Virol. 2012 86(3):1405-10. Kiso M, Ozawa M, Le MQ, Imai H, Takahashi K, Kakugawa S,
Noda T, Horimoto T, and Kawaoka Y: Effect of an asparagine-to-serine mutation at
position 294 in neuraminidase on the pathogenicity of highly pathogenic H5N1
influenza A virus. J Virol. 2011 85(10):860-866. Iwatsuki-Horimoto K, Horimoto T, Tamura D, Kiso M,
Kawakami E, Hatakeyama S, Ebihara Y, Koibuchi T, Fujii T, Takahashi K, Shimojima
M, Sakai-Tagawa Y, Ito M, Sakabe S, Iwasa A, Takahashi K, Ishii T, Gorai T,
Tsuji K, Iwamoto A, and Kawaoka Y: Sero-prevalence of pandemic (H1N1) 2009
influenza A virus among schoolchildren and their parents in Tokyo, Japan.
Clin
Vaccine Immunol. 2011 18(5):860-866. Akarsu H, Iwatsuki-Horimoto K, Noda T, Katsura H, Baudin
F, Horimoto T, and Kawaoka Y: Structure-based design of NS2 mutants for
attenuated influenza A virus vaccines. Virus Res. 2011 155(1):240-248. Horimoto T, Maeda K, Murakami S, Iwatsuki-Horimoto K, Ito
T, Suzuki K, Yokoyama M, and Kawaoka Y: Highly pathogenic avian influenza virus
infection in feral raccoons, Japan. Emerg Infect Dis. 2011 17(4):714-717. Sakabe S, Iwatsuki-Horimoto K, Takano R, Nidom CA, Le MT,
Nagamura-Inoue T, Horimoto T, Yamashita N, Kawaoka Y: Cytokine production by
primary human macrophages infected with highly pathogenic H5N1 or pandemic H1N1
2009 influenza viruses. J Gen Virol. 2011 92(Pt 6):1428-1434. Kurokawa H, Kato K, Iwanaga T, Sugi T, Sudo A, Kobayashi K, Gong H, Takemae H, Recuenco FC, Horimoto T, Akashi H. Identification of Toxoplasma gondii cAMP dependent protein kinase and its role in the tachyzoite growth.
PLoS One.
2011 6(7): e22492. Terasaki K, Murakami S, Lokugamage KG, Makino S. Mechanism of tripartite RNA genome packaging in Rift Valley fever virus.
Proc Natl Acad Sci U S A. 2011 108(2):804-9. Sugi T, Kato K, Kobayashi K, Kurokawa H, Takemae H, Gong
H, Recuenco FC, Iwanaga T, Horimoto T, Akashi H. 1NM-PP1 treatment of mice
infected with Toxoplasma gondii. J Vet Med Sci. 2011 73(10): 1377-1379. Haga T, Horimoto T. Animal Models to Study Influenza Virus
Pathogenesis and Control. The Open Antimicrobial Agents Journal. 2010 15-21. Horimoto T, Kawaoka Y. Pandemic Influenza. The Open Antimicrobial Agents
Journal. 2010 9-14.
Sakabe S, Iwatsuki-Horimoto K, Horimoto T, Nidom CA, Le Mt, Takano R,
Kubota-Koketsu R, Okuno Y, Ozawa M, Kawaoka Y. A cross-reactive neutralizing
monoclonal antibody protects mice from H5N1 and pandemic (H1N1) 2009 virus
infection. Antiviral Res. 2010 88(3):249-55.
Imai H, Shinya K, Takano R, Kiso M, Muramoto Y, Sakabe S, Murakami S, Ito M,
Yamada S, Le MT, Nidom CA, Sakai-Tagawa Y, Takahashi K, Omori Y, Noda T,
Shimojima M, Kakugawa S, Goto H, Iwatsuki-Horimoto K, Horimoto T, Kawaoka Y. The
HA and NS genes of human H5N1 influenza A virus contribute to high virulence in
ferrets. PLoS Pathog. 2010 6(9):e1001106.
Tamura D, Fujino M, Ozawa M, Iwatsuki-Horimoto K, Goto H, Sakai-Tagawa Y,
Horimoto T, Nirasawa M, Kawaoka Y. Significance of seasonal influenza viruses in
the stool of pediatric patients. Pediatr Infect Dis J. 2010 29(6):578-9.
Arii J, Goto H, Suenaga T, Oyama M, Kozuka-Hata H, Imai T, Minowa A, Akashi H,
Arase H, Kawaoka Y, Kawaguchi Y. Non-muscle myosin IIA is a functional entry
receptor for herpes simplex virus-1. Nature. 2010 467(7317):859-62.
Arii J, Wang J, Morimoto T, Suenaga T, Akashi H, Arase H, Kawaguchi Y. A
single-amino-acid substitution in herpes simplex virus 1 envelope glycoprotein B
at a site required for binding to the paired immunoglobulin-like type 2 receptor
alpha (PILRalpha) abrogates PILRalpha-dependent viral entry and reduces
pathogenesis. J Virol. 2010 84(20):10773-83.
Watanabe S, Masangkay JS, Nagata N, Morikawa S, Mizutani T, Fukushi S, Alviola
P, Omatsu T, Ueda N, Iha K, Taniguchi S, Fujii H, Tsuda S, Endoh M, Kato K,
Tohya Y, Kyuwa S, Yoshikawa Y, Akashi H. Bat coronaviruses and experimental
infection of bats, the Philippines. Emerg Infect Dis. 2010 Aug;16(8):1217-23.
Zahoor MA, Yamane D, Mohamed YM, Suda Y, Kobayashi K, Kato K, Tohya Y, Akashi H.
Bovine viral diarrhea virus non-structural protein 5A interacts with NIK- and
IKKbeta-binding protein. J Gen Virol. 2010 91(Pt 8):1939-48.
Azab W, Tsujimura K, Maeda K, Kobayashi K, Mohamed YM, Kato K, Matsumura T,
Akashi H. Glycoprotein C of equine herpesvirus 4 plays a role in viral binding
to cell surface heparan sulfate. Virus Res. 2010 151(1):1-9.
Watanabe S, Maeda K, Suzuki K, Ueda N, Iha K, Taniguchi S, Shimoda H, Kato K,
Yoshikawa Y, Morikawa S, Kurane I, Akashi H, Mizutani T. Novel betaherpesvirus
in bats. Emerg Infect Dis. 2010 16(6):986-8.
Fujii H, Watanabe S, Yamane D, Ueda N, Iha K, Taniguchi S, Kato K, Tohya Y,
Kyuwa S, Yoshikawa Y, Akashi H. Functional analysis of Rousettus aegyptiacus
"signal transducer and activator of transcription 1" (STAT1). Dev Comp Immunol.
2010 34(5):598-602.
Sugi T, Kato K, Kobayashi K, Watanabe S, Kurokawa H, Gong H, Pandey K, Takemae
H, Akashi H. Use of the kinase inhibitor analog 1NM-PP1 reveals a role for
Toxoplasma gondii CDPK1 in the invasion step. Eukaryot Cell. 2010 9(4):667-70.
Azab W, Tsujimura K, Kato K, Arii J, Morimoto T, Kawaguchi Y, Tohya Y, Matsumura
T, Akashi H. Characterization of a thymidine kinase-deficient mutant of equine
herpesvirus 4 and in vitro susceptibility of the virus to antiviral agents.
Antiviral Res. 2010 85(2):389-95.
Iha K, Omatsu T, Watanabe S, Ueda N, Taniguchi S, Fujii H, Ishii Y, Kyuwa S,
Akashi H, Yoshikawa Y. Molecular cloning and expression analysis of bat
toll-like receptors 3, 7 and 9.
Kobayashi K, Kato K, Sugi T, Takemae H, Pandey K, Gong H, Tohya Y, Akashi H.
Plasmodium falciparum BAEBL binds to heparan sulfate proteoglycans on the human
erythrocyte surface. J Biol Chem. 2010 285(3):1716-25.
Watanabe S, Omatsu T, Miranda ME, Masangkay JS, Ueda N, Endo M, Kato K, Tohya Y,
Yoshikawa Y, Akashi H. Epizootology and experimental infection of Yokose virus
in bats. Comp Immunol Microbiol Infect Dis. 2010 33(1):25-36.
Itoh Y, Shinya K, Kiso M, Watanabe T, Sakoda Y, Hatta M, Muramoto Y, Tamura D,
Sakai-Tagawa Y, Noda T, Sakabe S, Imai M, Hatta Y, Watanabe S, Li C, Yamada S,
Fujii K, Murakami S, Imai H, Kakugawa S, Ito M, Takano R, Iwatsuki-Horimoto K,
Shimojima M, Horimoto T, Goto H, Takahashi K, Makino A, Ishigaki H, Nakayama M,
Okamatsu M, Takahashi K, Warshauer D, Shult PA, Saito R, Suzuki H, Furuta Y,
Yamashita M, Mitamura K, Nakano K, Nakamura M, Brockman-Schneider R, Mitamura H,
Yamazaki M, Sugaya N, Suresh M, Ozawa M, Neumann G, Gern J, Kida H, Ogasawara K,
Kawaoka Y. In vitro and in vivo characterization of new swine-origin H1N1
influenza viruses. Nature. 2009 20;460(7258):1021-5.
Fujii K, Ozawa M, Iwatsuki-Horimoto K, Horimoto T,
Kawaoka Y. Incorporation of influenza A virus genome segments does not
absolutely require wild-type sequences. J Gen Virol. 2009
90(Pt
7):1734-40.
Tamura D, Mitamura K, Yamazaki M, Fujino M, Nirasawa M, Kimura K, Kiso M,
Shimizu H, Kawakami C, Hiroi S, Takahashi K, Hata M, Minagawa H, Kimura Y,
Kaneda S, Sugita S, Horimoto T, Sugaya N, Kawaoka Y. Oseltamivir-resistant
influenza a viruses circulating in Japan. J Clin Microbiol. 2009 47(5):1424-7.
Ozawa M, Maeda J, Iwatsuki-Horimoto K, Watanabe S, Goto H, Horimoto T, Kawaoka
Y. Nucleotide sequence requirements at the 5' end of the influenza A virus M RNA
segment for efficient virus replication. J Virol. 2009 Apr;83(7):3384-8.
Kakugawa S, Shimojima M, Goto H, Horimoto T, Oshimori N, Neumann G, Yamamoto T,
Kawaoka Y. Mitogen-activated protein kinase-activated kinase RSK2 plays a role
in innate immune responses to influenza virus infection. J Virol. 2009
83(6):2510-7.
Makino A, Horimoto T, Kawaoka Y. Binding properties of GP1 protein of Borna
disease virus. J Vet Med Sci. 2009 71(2):243-6.
Horimoto T, Kawaoka Y. Designing vaccines for pandemic influenza. Curr Top
Microbiol Immunol. 2009;333:165-76. Review.
Iha K, Omatsu T, Watanabe S, Ueda N, Taniguchi S, Fujii H, Ishii Y, Kyuwa S,
Akashi H, Yoshikawa Y. Molecular cloning and sequencing of the cDNAs encoding
the bat interleukin (IL)-2, IL-4, IL-6, IL-10, IL-12p40, and tumor necrosis
factor-alpha. J Vet Med Sci. 2009 71(12):1691-5.
Sugi T, Kato K, Kobayashi K, Pandey K, Takemae H, Kurokawa H, Tohya Y, Akashi H.
Molecular analyses of Toxoplasma gondii calmodulin-like domain protein kinase
isoform 3. Parasitol Int. 2009 58(4):416-23.
Kato K, Sudo A, Kobayashi K, Sugi T, Tohya Y, Akashi H. Characterization of
Plasmodium falciparum calcium-dependent protein kinase 4. Parasitol Int.
2009 58(4):394-400.
Morimoto T, Arii J, Tanaka M, Sata T, Akashi H, Yamada M, Nishiyama Y, Uema M,
Kawaguchi Y. Differences in the regulatory and functional effects of the Us3
protein kinase activities of herpes simplex virus 1 and 2. J Virol.
2009 83(22):11624-34.
Arii J, Kato K, Kawaguchi Y, Tohya Y, Akashi H. Analysis of herpesvirus host
specificity determinants using herpesvirus genomes as bacterial artificial
chromosomes. Microbiol Immunol. 2009 53(8):433-41.
Watanabe S, Ueda N, Iha K, Masangkay JS, Fujii H, Alviola P, Mizutani T, Maeda
K, Yamane D, Walid A, Kato K, Kyuwa S, Tohya Y, Yoshikawa Y, Akashi H. Detection
of a new bat gammaherpesvirus in the Philippines. Virus Genes.
2009 39(1):90-3.
Kobayashi K, Kato K, Sugi T, Yamane D, Shimojima M, Tohya Y, Akashi H.
Application of retrovirus-mediated expression cloning for receptor screening of
a parasite. Anal Biochem. 2009 389(1):80-2.
Yamane D, Zahoor MA, Mohamed YM, Azab W, Kato K, Tohya Y, Akashi H. Microarray
analysis reveals distinct signaling pathways transcriptionally activated by
infection with bovine viral diarrhea virus in different cell types.
Virus Res. 2009 142(1-2):188-99.
Yamane D, Zahoor MA, Mohamed YM, Azab W, Kato K, Tohya Y, Akashi H. Inhibition
of sphingosine kinase by bovine viral diarrhea virus NS3 is crucial for
efficient viral replication and cytopathogenesis. J Biol Chem.
2009 284(20):13648-59.
Arii J, Uema M, Morimoto T, Sagara H, Akashi H, Ono E, Arase H, Kawaguchi Y.
Entry of herpes simplex virus 1 and other alphaherpesviruses via the paired
immunoglobulin-like type 2 receptor alpha. J Virol. 2009
83(9):4520-7
Morimoto T, Arii J, Akashi H, Kawaguchi Y. Identification of multiple sites
suitable for insertion of foreign genes in herpes simplex virus genomes.
Microbiol Immunol. 2009 (3):155-61.
Zahoor MA, Yamane D, Mohamed YM, Kobayashi K, Kato K, Tohya Y, Akashi H.
Characterization and application of monoclonal antibodies to bovine viral
diarrhea virus nonstructural protein 5A. Arch Virol. 2009
154(11):1745-54.
Yamane D, Zahoor MA, Mohamed YM, Azab W, Kato K, Tohya Y, Akashi H. Activation
of extracellular signal-regulated kinase in MDBK cells infected with bovine
viral diarrhea virus. Arch Virol. 2009 154(9):1499-503.
Azab W, Kato K, Arii J, Tsujimura K, Yamane D, Tohya Y, Matsumura T, Akashi H.
Cloning of the genome of equine herpesvirus 4 strain TH20p as an infectious
bacterial artificial chromosome. Arch Virol. 2009
154(5):833-42.
Yamao T, Eshita Y, Kihara Y, Satho T, Kuroda M, Sekizuka T, Nishimura M, Sakai
K, Watanabe S, Akashi H, Rongsriyam Y, Komalamisra N, Srisawat R, Miyata T,
Sakata A, Hosokawa M, Nakashima M, Kashige N, Miake F, Fukushi S, Nakauchi M,
Saijo M, Kurane I, Morikawa S, Mizutani T. Novel virus discovery in
field-collected mosquito larvae using an improved system for rapid determination
of viral RNA sequences (RDV ver4.0). Arch Virol. 2009
154(1):153-8.
Kato A, Arii J, Shiratori I, Akashi H, Arase H, Kawaguchi Y. Herpes simplex
virus 1 protein kinase Us3 phosphorylates viral envelope glycoprotein B and
regulates its expression on the cell surface. J Virol. 2009
83(1):250-61.
Murakami S, Iwasa A, Iwatsuki-Horimoto K, Ito M, Kiso M, Kida H, Takada A, Nidom
CA, Mai le Q, Yamada S, Imai H, Sakai-Tagawa Y, Kawaoka Y, Horimoto T.
Cross-clade protective immunity of H5N1 influenza vaccines in a mouse model.
Vaccine. 2008 26(50):6398-404.
Murakami S, Horimoto T, Mai le Q, Nidom CA, Chen H, Muramoto Y, Yamada S, Iwasa
A, Iwatsuki-Horimoto K, Shimojima M, Iwata A, Kawaoka Y. Growth determinants for
H5N1 influenza vaccine seed viruses in MDCK cells. J Virol. 2008 82(21):10502-9.
Iwatsuki-Horimoto K, Hatta Y, Hatta M, Muramoto Y, Chen H, Kawaoka Y, Horimoto
T. Limited compatibility between the RNA polymerase components of influenza
virus type A and B. Virus Res. 2008 135(1):161-5.
Song JH, Nguyen HH, Cuburu N, Horimoto T, Ko SY, Park SH, Czerkinsky C, Kweon
MN. Sublingual vaccination with influenza virus protects mice against lethal
viral infection. Proc Natl Acad Sci U S A. 2008 105(5):1644-9.
Murakami S, Horimoto T, Yamada S, Kakugawa S, Goto H, Kawaoka Y. Establishment
of canine RNA polymerase I-driven reverse genetics for influenza A virus: its
application for H5N1 vaccine production. J Virol. 2008 82(3):1605-9.
Ogawa Y, Sugiura K, Kato K, Tohya Y, Akashi H. Rescue of Akabane virus (family
Bunyaviridae) entirely from cloned cDNAs by using RNA polymerase I. J
Gen Virol. 2007 88(Pt 12):3385-90.
Ogawa Y, Fukutomi T, Sugiura K, Sugiura K, Kato K, Tohya Y, Akashi H. Comparison
of Akabane virus isolated from sentinel cattle in Japan. Vet Microbiol.
2007 124(1-2):16-24.
Omatsu T, Watanabe S, Akashi H, Yoshikawa Y. Biological characters of bats in
relation to natural reservoir of emerging viruses. Comp Immunol
Microbiol Infect Dis. 2007 30(5-6):357-74.
Horimoto T, Murakami S, Muramoto Y, Yamada S, Fujii K, Kiso M, Iwatsuki-Horimoto
K, Kino Y, Kawaoka Y. Enhanced growth of seed viruses for H5N1 influenza
vaccines. Virology. 2007 366(1):23-7.
Ozawa M, Goto H, Horimoto T, Kawaoka Y. An adenovirus vector-mediated reverse
genetics system for influenza A virus generation. J Virol. 2007 81(17):9556-9.
Youn HJ, Ko SY, Lee KA, Ko HJ, Lee YS, Fujihashi K, Boyaka PN, Kim SH, Horimoto
T, Kweon MN, Kang CY. A single intranasal immunization with inactivated
influenza virus and alpha-galactosylceramide induces long-term protective
immunity without redirecting antigen to the central nervous system. Vaccine.
2007 25(28):5189-98.
Ozawa M, Fujii K, Muramoto Y, Yamada S, Yamayoshi S, Takada A, Goto H, Horimoto
T, Kawaoka Y. Contributions of two nuclear localization signals of influenza A
virus nucleoprotein to viral replication. J Virol. 2007 81(1):30-41.
Yamane D, Kato K, Tohya Y, Akashi H. The double-stranded RNA-induced apoptosis
pathway is involved in the cytopathogenicity of cytopathogenic Bovine viral
diarrhea virus. J Gen Virol. 2006 87(Pt 10):2961-70.
Omatsu T, Nishimura Y, Bak EJ, Ishii Y, Tohya Y, Kyuwa S, Akashi H, Yoshikawa Y.
Molecular cloning and sequencing of the cDNA encoding the bat CD4.Vet
Immunol Immunopathol. 2006 111(3-4):309-13.
Makino A, Shimojima M, Miyazawa T, Kato K, Tohya Y, Akashi H. Junctional
adhesion molecule 1 is a functional receptor for feline calicivirus. J
Virol. 2006 80(9):4482-90.
Arii J, Hushur O, Kato K, Kawaguchi Y, Tohya Y, Akashi H. Construction of an
infectious clone of canine herpesvirus genome as a bacterial artificial
chromosome. Microbes Infect. 2006 8(4):1054-63.
Okuda Y, Ono M, Shibata I, Sato S, Akashi H. Comparison of the polymerase chain
reaction-restriction fragment length polymorphism pattern of the fiber gene and
pathogenicity of serotype-1 fowl adenovirus isolates from gizzard erosions and
from feces of clinically healthy chickens in Japan. J Vet Diagn Invest.
2006 18(2):162-7.
Yamada S, Suzuki Y, Suzuki T, Le MQ, Nidom CA, Sakai-Tagawa Y, Muramoto Y, Ito
M, Kiso M, Horimoto T, Shinya K, Sawada T, Kiso M, Usui T, Murata T, Lin Y, Hay
A, Haire LF, Stevens DJ, Russell RJ, Gamblin SJ, Skehel JJ, Kawaoka Y.
Haemagglutinin mutations responsible for the binding of H5N1 influenza A viruses
to human-type receptors. Nature. 2006 444(7117):378-82.
Horimoto T, Kawaoka Y. Strategies for developing vaccines against H5N1 influenza
A viruses. Trends Mol Med. 2006 12(11):506-14. Review.
Muramoto Y, Le TQ, Phuong LS, Nguyen T, Nguyen TH, Sakai-Tagawa Y, Horimoto T,
Kida H, Kawaoka Y. Pathogenicity of H5N1 influenza A viruses isolated in Vietnam
between late 2003 and 2005. J Vet Med Sci. 2006 68(7):735-7.
Iwatsuki-Horimoto K, Horimoto T, Noda T, Kiso M, Maeda J, Watanabe S, Muramoto
Y, Fujii K, Kawaoka Y. The cytoplasmic tail of the influenza A virus M2 protein
plays a role in viral assembly. J Virol. 2006 80(11):5233-40.
Muramoto Y, Le TQ, Phuong LS, Nguyen T, Nguyen TH, Sakai-Tagawa Y,
Iwatsuki-Horimoto K, Horimoto T, Kida H, Kawaoka Y. Molecular characterization
of the hemagglutinin and neuraminidase genes of H5N1 influenza A viruses
isolated from poultry in Vietnam from 2004 to 2005. J Vet Med Sci. 2006
68(5):527-31.
Horimoto T, Takada A, Fujii K, Goto H, Hatta M, Watanabe S, Iwatsuki-Horimoto K,
Ito M, Tagawa-Sakai Y, Yamada S, Ito H, Ito T, Imai M, Itamura S, Odagiri T,
Tashiro M, Lim W, Guan Y, Peiris M, Kawaoka Y. The development and
characterization of H5 influenza virus vaccines derived from a 2003 human
isolate. Vaccine. 2006 24(17):3669-76.
Muramoto Y, Takada A, Fujii K, Noda T, Iwatsuki-Horimoto K, Watanabe S, Horimoto
T, Kida H, Kawaoka Y. Hierarchy among viral RNA (vRNA) segments in their role in
vRNA incorporation into influenza A virions. J Virol. 2006 80(5):2318-25.
Le QM, Kiso M, Someya K, Sakai YT, Nguyen TH, Nguyen KH, Pham ND, Ngyen HH,
Yamada S, Muramoto Y, Horimoto T, Takada A, Goto H, Suzuki T, Suzuki Y, Kawaoka
Y. Avian flu: isolation of drug-resistant H5N1 virus. Nature. 2005
437(7062):1108.
Mase M, Eto M, Tanimura N, Imai K, Tsukamoto K, Horimoto T, Kawaoka Y, Yamaguchi
S. Isolation of a genotypically unique H5N1 influenza virus from duck meat
imported into Japan from China. Virology. 2005 339(1):101-9.
Shinya K, Hatta M, Yamada S, Takada A, Watanabe S, Halfmann P, Horimoto T,
Neumann G, Kim JH, Lim W, Guan Y, Peiris M, Kiso M, Suzuki T, Suzuki Y, Kawaoka
Y. Characterization of a human H5N1 influenza A virus isolated in 2003. J Virol.
2005 79(15):9926-32.
Horimoto T, Kawaoka Y. Influenza: lessons from past pandemics, warnings from
current incidents. Nat Rev Microbiol. 2005 3(8):591-600. Review.
Fujii K, Fujii Y, Noda T, Muramoto Y, Watanabe T, Takada A, Goto H, Horimoto T,
Kawaoka Y. Importance of both the coding and the segment-specific noncoding
regions of the influenza A virus NS segment for its efficient incorporation into
virions. J Virol. 2005 Mar;79(6):3766-74.
Mase M, Tsukamoto K, Imada T, Imai K, Tanimura N, Nakamura K, Yamamoto Y, Hitomi
T, Kira T, Nakai T, Kiso M, Horimoto T, Kawaoka Y, Yamaguchi S. Characterization
of H5N1 influenza A viruses isolated during the 2003-2004 influenza outbreaks in
Japan. Virology. 2005 332(1):167-76.
Phung HT, Tohya Y, Miyazawa T, Akashi H. Characterization of Env antigenicity of
feline foamy virus (FeFV) using FeFV-infected cat sera and a monoclonal
antibody. Vet Microbiol. 2005 106(3-4):201-7.
Hamano M, Maeda K, Kai K, Mochizuki M, Tohya Y, Akashi H. A novel genetic marker
to differentiate feline herpesvirus type 1 field isolates. Vet
Microbiol. 2005 106(3-4):195-200.
Iwatsuki-Horimoto K, Horimoto T, Fujii Y, Kawaoka Y. Generation of influenza A
virus NS2 (NEP) mutants with an altered nuclear export signal sequence. J Virol.
2004 78(18):10149-55.
Horimoto T, Takada A, Iwatsuki-Horimoto K, Kawaoka Y. A protective immune
response in mice to viral components other than hemagglutinin in a live
influenza A virus vaccine model. Vaccine. 2004 22(17-18):2244-7.
Horimoto T, Iwatsuki-Horimoto K, Hatta M, Kawaoka Y. Influenza A viruses
possessing type B hemagglutinin and neuraminidase: potential as vaccine
components. Microbes Infect. 2004 6(6):579-83.
Iwatsuki-Horimoto K, Kanazawa R, Sugii S, Kawaoka Y, Horimoto T. The index
influenza A virus subtype H5N1 isolated from a human in 1997 differs in its
receptor-binding properties from a virulent avian influenza virus. J Gen Virol.
2004 85(Pt 4):1001-5.
Maeda Y, Goto H, Horimoto T, Takada A, Kawaoka Y. Biological significance of the
U residue at the -3 position of the mRNA sequences of influenza A viral segments
PB1 and NA. Virus Res. 2004 100(2):153-7
Horimoto T, Fukuda N, Iwatsuki-Horimoto K, Guan Y, Lim W, Peiris M, Sugii S,
Odagiri T, Tashiro M, Kawaoka Y. Antigenic differences between H5N1 human
influenza viruses isolated in 1997 and 2003. J Vet Med Sci. 2004 66(3):303-5.
Kondo T, McGregor M, Chu Q, Chen D, Horimoto T, Kawaoka Y. A protective effect
of epidermal powder immunization in a mouse model of equine herpesvirus-1
infection. Virology. 2004 318(1):414-9.
Ichimura N, Shimojima M, Nishimura Y, Tohya Y, Akashi H. Molecular cloning and
sequencing of feline CD7.
J Vet Med Sci.
2004 66(10):1255-8.
Sakurai Y, Shimojima M, Miyazawa T, Masuoka K, Tohya Y, Akashi H. Identification
of the feline CD63 homologue using retrovirus-mediated expression cloning.
Vet Immunol Immunopathol. 2004 98(3-4):185-91.
Shimojima M, Nishimura Y, Miyazawa T, Tohya Y, Akashi H. T cell subpopulations
mediating inhibition of feline immunodeficiency virus replication in mucosally
infected cats. Microbes Infect. 2004 6(3):265-71.
Shimojima M, Miyazawa T, Ikeda Y, McMonagle EL, Haining H, Akashi H, Takeuchi Y,
Hosie MJ, Willett BJ. Use of CD134 as a primary receptor by the feline
immunodeficiency virus. Science. 2004 303(5661):1192-5.
Nagai M, Hayashi M, Sugita S, Sakoda Y, Mori M, Murakami T, Ozawa T, Yamada N,
Akashi H. Phylogenetic analysis of bovine viral diarrhea viruses using five
different genetic regions. Virus Res. 2004 99(2):103-13.
Horimoto T, Takada A, Iwatsuki-Horimoto K, Hatta M, Goto H, Kawaoka Y.
Generation of influenza A viruses with chimeric (type A/B) hemagglutinins.
J
Virol. 2003 77(14):8031-8.
Kato K, Yokoyama A, Tohya Y, Akashi H, Nishiyama Y, Kawaguchi Y.
Identification of protein kinases responsible for phosphorylation of
Epstein-Barr virus nuclear antigen leader protein at serine-35, which regulates
its coactivator function. J Gen Virol. 2003 84(Pt 12):3381-92.
Nakamura M, Nakamura K, Miyazawa T, Tohya Y, Mochizuki M, Akashi H. Monoclonal
antibodies that distinguish antigenic variants of canine parvovirus.
Clin Diagn Lab Immunol. 2003 10(6):1085-9.
Shimojima M, Nishimura Y, Miyazawa T, Tohya Y, Akashi H. Phenotypic changes in
CD8+ peripheral blood lymphocytes in cats infected with feline immunodeficiency
virus. Microbes Infect. 2003 5(13):1171-6.
Hamano M, Maeda K, Mizukoshi F, Une Y, Mochizuki M, Tohya Y, Akashi H, Kai K.
Experimental infection of recent field isolates of feline herpesvirus type 1.
J Vet Med Sci. 2003 65(8):939-43.
Shimojima M, Nishimura Y, Miyazawa T, Kato K, Tohya Y, Akashi H. CD56 expression
in feline lymphoid cells. J Vet Med Sci. 2003 65(7):769-73.
Tsushima Y, Karanis P, Kamada T, Xuan X, Makala LH, Tohya Y, Akashi H, Nagasawa
H. Viability and infectivity of Cryptosporidium parvum oocysts detected in river
water in Hokkaido, Japan. J Vet Med Sci. 2003 65(5):585-9.
Phung HT, Tohya Y, Shimojima M, Kato K, Miyazawa T, Akashi H. Establishment of a
GFP-based indicator cell line to quantitate feline foamy virus. J Virol
Methods. 2003 109(2):125-31.
Shimojima M, Miyazawa T, Sakurai Y, Nishimura Y, Tohya Y, Matsuura Y, Akashi H.
Usage of myeloma and panning in retrovirus-mediated expression cloning.
Anal Biochem. 2003 315(1):138-40.
Nagai M, Sakoda Y, Mori M, Hayashi M, Kida H, Akashi H. Insertion of cellular
sequence and RNA recombination in the structural protein coding region of
cytopathogenic bovine viral diarrhoea virus. J Gen Virol. 2003
84(Pt 2):447-52.
Tsushima Y, Karanis P, Kamada T, Makala L, Xuan X, Tohya Y, Akashi H, Nagasawa
H. Seasonal change in the number of Cryptosporidium parvum oocysts in water
samples from the rivers in Hokkaido, Japan, detected by the ferric sulfate
flocculation method. J Vet Med Sci. 2003 65(1):121-3.
Ito T, Kobayashi Y, Morita T, Horimoto T, Kawaoka Y. Virulent influenza A
viruses induce apoptosis in chickens. Virus Res. 2002 84(1-2):27-35.
Shimojima M, Nishimura Y, Miyazawa T, Kato K, Nakamura K, Izumiya Y, Akashi H,
Tohya Y. A feline CD2 homologue interacts with human red blood cells.
Immunology. 2002 105(3):360-6.