発表論文

2022

Murakami S, Kitamura T, Matsugo H, Kamiki H, Oyabu K, Sekine W, Takenaka-Uema A, Sakai-Tagawa Y, Kawaoka Y, Horimoto T. Isolation of Bat Sarbecoviruses, Japan. Emerg Infect Dis. 2022 28(12):2500-2503.

Murakami S, Kitamura T, Matsugo H, Yamamoto T, Mineshita K, Sakuyama M, Sasaki R, Takenaka-Uema A, Horimoto T. Detection and genetic characterization of bat MERS-related coronaviruses in Japan. Transbound Emerg Dis. 2022 in press

Kamiki H, Murakami S, Nishikaze T, Hiono T, Igarashi M, Furuse Y, Matsugo H, Ishida H, Katayama M, Sekine W, Muraki Y, Takahashi M, Takenaka-Uema A, Horimoto T. Influenza A Virus Agnostic Receptor Tropism Revealed Using a Novel Biological System with Terminal Sialic Acid Knockout Cells. J Virol. 2022 96(15):e0041622.

Sekine W, Takenaka-Uema A, Kamiki H, Ishida H, Matsugo H, Murakami S, Horimoto T. Adaptation of the H7N2 Feline Influenza Virus to Human Respiratory Cell Culture. Adaptation of the H7N2 Feline Influenza Virus to Human Respiratory Cell Culture. Viruses. 2022 14(5):1091.

Takenaka-Uema A, Matsugo H, Ohira K, Sekine W, Murakami S, Horimoto T. Different organ and tissue tropism between Akabane virus genogroups in a mouse model. Virus Res. 2022 314:198752.

Katayama M,Murakami S, Matsugo H, Kamiki H, Fujii M, Takenaka-Uema A, Horimoto T. Complete genome sequence of a novel bat mastadenovirus C strain isolated from Rhinolophus cornutus in Japan. Arch Virol. 2022 167(3):979-982.

2021

Matsugo H, Kitamura-Kobayashi T, Kamiki H, Ishida H, Sekine W, Takenaka-Uema A, Nakagawa T, Murakami S, Horimoto T. A potential bat adenovirus-based oncolytic virus targeting canine cancers. Sci Rep. 2021 11(1):16706.

Ishida H, Murakami S, Kamiki H, Matsugo H, Katayama M, Sekine W, Ohira K, Takenaka-Uema A, Horimoto T. Construction of an Influenza D Virus with an Eight-Segmented Genome. Viruses. 2021 13(11):2166.

Kuroda Y, Okada A, Shimoda H, Miwa Y, Watamori A, Ishida H, Murakami S, Takada A,Horimoto T, Maeda K. Influenza A virus infection in domestic ferrets. Jpn J Infect Dis. 2021.

2020

Murakami S, Kitamura T, Suzuki J, Sato R, Aoi T, Fujii M, Matsugo H, Kamiki H, Ishida H, Takenaka-Uema A, Shimojima M, Horimoto T. Detection and Characterization of Bat Sarbecovirus Phylogenetically Related to SARS-CoV-2, Japan. Emerg Infect Dis. 2020 26(12):3025-3029.

Matsugo H, Kobayashi-Kitamura T, Kamiki H, Ishida H, Takenaka-Uema A,Murakami S, Horimoto T. Establishment of a Simple and Efficient Reverse Genetics System for Canine Adenoviruses Using Bacterial Artificial Chromosomes. Viruses 2020 12(7):767.

Wan XF, Ferguson L, Oliva J, Rubrum A, Eckard L, Zhang X, Woolums AR, Lion A, Meyer G,Murakami S, Horimoto T, Webby R, Ducatez MF, Epperson W. Limited Cross-Protection Provided by Prior Infection Contributes to High Prevalence of Influenza D Viruses in Cattle. J Virol. 2020 94(18):e00240-20.

Ishida H, Murakami S, Kamiki H, Matsugo H, Takenaka-Uema A, Horimoto T. Establishment of a Reverse Genetics System for Influenza D Virus. J Virol. 2020 94(10):e01767-19.

Murakami S, Odagiri T, Melaku SK, Bazartseren B, Ishida H, Takenaka-Uema A, Muraki Y, Sentsui H, Horimoto T. Influenza D Virus Infection in Dromedary Camels, Ethiopia. Emerg Infect Dis. 2019, 25(6):1224-1226.

Suda Y, Murakami S, Horimoto T. Bovine viral diarrhea virus non-structural protein NS4B induces autophagosomes in bovine kidney cells. Arch Virol. 2019, 164(1):255-260.

Kobayashi T, Matsugo H, Maruyama J, Kamiki H, Takada A, Maeda K, Takenaka-Uema A, Murakami S, Horimoto T. Characterization of a Novel Species Bat Adenovirus from Japanese Microbat and Responsibility of CXADR as Its Functional Receptor. Sci Rep. 2019 9(1): 573.

 

2018

Takemae H, Kobayashi K, Sugi T, Han Y, Gong H, Ishiwa A, Recuenco FC, Murakoshi F, Takano R, Murata Y, Nagamune K, Horimoto T, Akashi H, Kato K. Toxoplasma gondii RON4 binds to heparan sulfate on the host cell surface. Parasitol Int. 2018 67(2):123-130.

Kamiki H, Matsugo H, Kobayashi T, Ishida H, Takenaka-Uema A, Murakami S, Horimoto T. A PB1-K577E mutation in H9N2 influenza virus increases polymerase activity and pathogenicity in mice. Viruses. 10, 653, 2018

Odagiri T, Ishida H, Li JY, Endo M, Kobayashi T, Kamiki H, Matsugo H, Takenaka-Uema A, Murakami S, Horimoto T. Antigenic heterogeneity among phylogenetic clusters of influenza D viruses. J Vet Med Sci. 2018  80(8):1241-1244.

Kobayashi T, Murakami S, Yamamoto T, Mineshita K, Sakuyama M, Sasaki R, Maeda K, Horimoto T. Detection of bat hepatitis E virus RNA in microbats in Japan. Virus Genes. 2018 54(4):599-602.

Suda Y, Chamberlain J, Dowall SD, Saijo M, Horimoto T, Hewson R, Shimojima M. The Development of a Novel Diagnostic Assay That Utilizes a Pseudotyped Vesicular Stomatitis Virus for the Detection of Neutralizing Activity against Crimean-Congo Hemorrhagic Fever Virus. Jpn J Infect Dis. 2018 71(3):205-208.

Nakatsu S, Murakami S, Shindo K, Horimoto T, Sagara H, Noda T, Kawaoka Y. Influenza C and D viruses package eight organized ribonucleoprotein complexes. J Virol. 2018 92(6). pii: e02084-17

Noda T*, Murakami S* (*contributed equally), Nakatsu S, Imai H, Muramoto Y, Shindo K, Sagara H, Kawaoka Y. Importance of the 1+7 configuration of ribonucleoprotein complexes for influenza A virus genome packaging. Nat Commun. 2018 9(1):54.

 

2017

Murakami S, Takenaka-Uema A, Kobayashi T, Kato K, Shimojima M, Palmarini M, Horimoto T. Heparan Sulfate Proteoglycan Is an Important Attachment Factor for Cell Entry of Akabane and Schmallenberg Viruses. J Virol. 2017 91(15).

Ui H, Yamayoshi S, Uraki R, Kiso M, Oishi K, Murakami S, Mimori S, Kawaoka Y. Evaluation of seasonal influenza vaccines for H1N1pdm09 and type B viruses based on a replication-incompetent PB2-KO virus. Vaccine. 2017 35(15):1892-1897.

Shimoda H, VAN Nguyen D, Yonemitsu K, Minami S, Nagata N, Hara N, Kuwata R, Murakami S, Kodera Y, Takeda T, Yoshikawa Y, Horimoto T, Maeda K. Influenza A virus infection in Japanese wild boars (Sus scrofa leucomystax). J Vet Med Sci. 2017 79(5):848-851.

Taniguchi S, Maeda K, Horimoto T, Masangkay JS, Puentespina R Jr, Alvarez J, Eres E, Cosico E, Nagata N, Egawa K, Singh H, Fukuma A, Yoshikawa T, Tani H, Fukushi S, Tsuchiaka S, Omatsu T, Mizutani T, Une Y, Yoshikawa Y, Shimojima M, Saijo M, Kyuwa S. First isolation and characterization of pteropine orthoreoviruses in fruit bats in the Philippines. Arch Virol. 2017 162(6):1529-1539.

Recuenco FC, Takano R, Sugi T, Takemae H, Murakoshi F, Ishiwa A, Inomata A, Enomoto-Rogers Y, Fundador NGV, Iwata T, Horimoto T, Akashi H, Kato K. Assessment of the growth inhibitory effect of gellan sulfate in rodent malaria in vivo. Jap J Vet Res 2017 65(4):207-212.

2016

Horimoto T, Hiono T, Mekata H, Odagiri T, Lei Z, Kobayashi T, Norimine J, Inoshima Y, Hikono H, Murakami K, Sato R, Murakami H, Sakaguchi M, Ishii K, Ando T, Otomaru K, Ozawa M, Sakoda Y, Murakami S. Nationwide Distribution of Bovine Influenza D Virus Infection in Japan. PLoS One. 2016 11(9):e0163828.

Gong H, Kobayashi K, Sugi T, Takemae H, Horimoto T, Xuan X, Akashi H, Kato K. Pull-down method to access the cell surface receptor for Toxoplasma gondii. Parasitol Int. 2016 65(5 Pt B):514-515.

Kato K, Sugi T, Takemae H, Takano R, Gong H, Ishiwa A, Horimoto T, Akashi H. Characterization of a Toxoplasma gondii calcium calmodulin-dependent protein kinase homolog. Parasit Vectors. 2016 9(1):405.

Murakami S, Endoh M, Kobayashi T, Takenaka-Uema A, Chambers JK, Uchida K, Nishihara M, Hause B, Horimoto T. Influenza D Virus Infection in Herd of Cattle, Japan. Emerg Infect Dis. 2016 (8):1517-9.

Ishihara Y, Shioda C, Bangphoomi N, Sugiura K, Saeki K, Tsuda S, Iwanaga T, Takenaka-Uema A, Kato K, Murakami S, Uchida K, Akashi H, Horimoto T. Akabane virus nonstructural protein NSm regulates viral growth and pathogenicity in a mouse model. J Vet Med Sci. 2016 78(9):1391-1397.
 

Gong H, Kobayashi K, Sugi T, Takemae H, Horimoto T, Xuan X, Akashi H, Kato K. Pull-down method to access the cell surface receptor for Toxoplasma gondii. Parasitol Int. 2016 65(5 Pt B):514-515.

Kato K, Sugi T, Takemae H, Takano R, Gong H, Ishiwa A, Horimoto T, Akashi H. Characterization of a Toxoplasma gondii calcium calmodulin-dependent protein kinase homolog. Parasit Vectors. 2016 9(1):405.

Suda Y, Fukushi S, Tani H, Murakami S, Saijo M, Horimoto T, Shimojima M. Analysis of the entry mechanism of Crimean-Congo hemorrhagic fever virus, using a vesicular stomatitis virus pseudotyping system. Arch Virol. 2016 161(6):1447-54.

Takenaka-Uema A, Sugiura K, Bangphoomi N, Shioda C, Uchida K, Kato K, Haga T, Murakami S, Akashi H, Horimoto T. Development of an improved reverse genetics system for Akabane bunyavirus. J Virol Methods. 2016 232:16-20.

Murakoshi F, Ichikawa-Seki M, Aita J, Yaita S, Kinami A, Fujimoto K, Nishikawa Y, Murakami S, Horimoto T, Kato K. Molecular epidemiological analyses of Cryptosporidium parvum virus 1 (CSpV1), a symbiotic virus of Cryptosporidium parvum, in Japan. Virus Res. 2016 211:69-72.

Murakami S, Terasaki K, Makino S. Generation of a Single-Cycle Replicable Rift Valley Fever Vaccine. Methods Mol Biol. 2016 1403:187-206.

 

2015

Takenaka-Uema A, Murata Y, Gen F, Ishihara-Saeki Y, Watanabe K, Uchida K, Kato K, Murakami S, Haga T, Akashi H, Horimoto T. Generation of a Recombinant Akabane Virus Expressing Enhanced Green Fluorescent Protein. J Virol. 2015 89(18):9477-84.

Inomata A, Murakoshi F, Ishiwa A, Takano R, Takemae H, Sugi T, Cagayat Recuenco F, Horimoto T, Kato K. Heparin interacts with elongation factor 1α of Cryptosporidium parvum and inhibits invasion. Sci Rep. 2015 5:11599.

Horimoto T, Gen F, Murakami S, Iwatsuki-Horimoto K, Kato K, Hisasue M, Sakaguchi M, Nidom CA, Kawaoka Y. Cats as a potential source of emerging influenza virus infections. Virol Sin. 2015 30(3):221-3.

Yamayoshi S, Fukuyama S, Yamada S, Zhao D, Murakami S, Uraki R, Watanabe T, Tomita Y, Neumann G, Kawaoka Y. Amino acids substitutions in the PB2 protein of H7N9 influenza A viruses are important for virulence in mammalian hosts. Sci Rep. 2015 5:8039. 

 

2014

Murakami S, Terasaki K, Ramirez SI, Morrill JC, Makino S. Development of a novel, single-cycle replicable Rift Valley fever vaccine. PLoS Negl Trop Dis. 2014 8(3):e2746.

Yamayoshi S, Yamada S, Fukuyama S, Murakami S, Zhao D, Uraki R, Watanabe T, Tomita Y, Macken C, Neumann G, Kawaoka Y. Virulence-affecting amino acid changes in the PA protein of H7N9 Influenza A viruses. J Virol. 2014 88(6):3127-34.

Mohamed YM, Bangphoomi N, Yamane D, Suda Y, Kato K, Horimoto T, Akashi H. Physical interaction between bovine viral diarrhea virus nonstructural protein 4A and adenosine deaminase acting on RNA (ADAR). Arch Virol. 2014 159(7):1735-41.

Bangphoomi N, Takenaka-Uema A, Sugi T, Kato K, Akashi H, Horimoto T. Akabane virus utilizes alternative endocytic pathways to entry into mammalian cell lines. J Vet Med Sci. 2014 76(11):1471-8.

Katsura H, Piao Z, Iwatsuki-Horimoto K, Akeda Y, Watanabe S, Horimoto T, Oishi K, Kawaoka Y. A bivalent vaccine based on a replication-incompetent influenza virus protects against Streptococcus pneumoniae and influenza virus infection. J Virol. 2014 88(22):13410-7.

Recuenco FC, Takano R, Chiba S, Sugi T, Takemae H, Murakoshi F, Ishiwa A, Inomata A, Horimoto T, Kobayashi Y, Horiuchi N, Kato K. Lambda-carrageenan treatment exacerbates the severity of cerebral malaria caused by Plasmodium berghei ANKA in BALB/c mice. Malar J. 2014 13:487.

Takemae H, Sugi T, Kobayashi K, Murakoshi F, Recuenco FC, Ishiwa A, Inomata A, Horimoto T, Yokoyama N, Kato K, Kato K. Interaction between Theileria orientalis 23-kDa piroplasm membrane protein and heparin. Jpn J Vet Res. 2014 62(1-2):17-24.

Recuenco FC, Kobayashi K, Ishiwa A, Enomoto-Rogers Y, Fundador NG, Sugi T, Takemae H, Iwanaga T, Murakoshi F, Gong H, Inomata A, Horimoto T, Iwata T, Kato K. Gellan sulfate inhibits Plasmodium falciparum growth and invasion of red blood cells in vitro. Sci Rep. 2014 4:4723.

Gong H, Kobayashi K, Sugi T, Takemae H, Ishiwa A, Recuenco FC, Murakoshi F, Xuan X, Horimoto T, Akashi H, Kato K. Characterization and binding analysis of a microneme adhesive repeat domain-containing protein from Toxoplasma gondii. Parasitol Int. 2014 63(2):381-8.

Horimoto T, Gen F, Murakami S, Iwatsuki-Horimoto K, Kato K, Akashi H, Hisasue M, Sakaguchi M, Kawaoka Y, Maeda K. Serological evidence of infection of dogs with human influenza viruses in Japan. Vet Rec. 2014 174(4):96.

 

2013

Watanabe T, Kiso M, Fukuyama S, Nakajima N, Imai M, Yamada S, Murakami S, Yamayoshi S, Iwatsuki-Horimoto K, Sakoda Y, Takashita E, McBride R, Noda T, Hatta M, Imai H, Zhao D, Kishida N, Shirakura M, de Vries RP, Shichinohe S, Okamatsu M, Tamura T, Tomita Y, Fujimoto N, Goto K, Katsura H, Kawakami E, Ishikawa I, Watanabe S, Ito M, Sakai-Tagawa Y, Sugita Y, Uraki R, Yamaji R, Eisfeld AJ, Zhong G, Fan S, Ping J, Maher EA, Hanson A, Uchida Y, Saito T, Ozawa M, Neumann G, Kida H, Odagiri T, Paulson JC, Hasegawa H, Tashiro M, Kawaoka Y.,Characterization of H7N9 influenza A viruses isolated from humans.Nature. 2013 26;501(7468):551-5.

Takemae H, Sugi T, Kobayashi K, Gong H, Ishiwa A, Recuenco FC, Murakoshi F, Iwanaga T, Inomata A, Horimoto T, Akashi H, Kato K: Characterization of the interaction between Toxoplasma gondii rhoptry neck protein 4 and host cellular β-tubulin. Sci Rep 3:3199, 2013.

Ishiwa A, Kobayashi K, Takemae H, Sugi T, Gong H, Recuenco FC, Murakoshi F, Inomata A, Horimoto T, Kato K. Effects of dextran sulfates on the acute infection and growth stages of Toxoplasma gondii. Parasitol Res. 2013 112: 4169-4176, .

Sugi T, Kobayashi K, Takemae H, Gong H, Ishiwa A, Murakoshi F, Recuenco FC, Iwanaga T, Horimoto T, Akashi H, Kato K. Identification of mutations in TgMAPK1 of Toxoplasma gondii conferring resistance to 1NM-PP1. International J Parasit. 2013 3:93-101.

Takemae H, Sugi T, Kobayashi K, Gong H, Ishiwa A, Recuenco FC, Murakoshi F, Iwanaga T, Inomata A, Horimoto T, Akashi H, Kato K. Toxoplasma gondii RON4 binds to heparan sulfate of host cell surface. Sci Rep. 2013 3: 3199.

Kobayashi K, Takano R, Takemae H, Sugi T, Ishiwa R, Gong H, Recuenco FC, Iwanaga T, Horimoto T, Akashi H, Kato K. Analyses of interactions between heparin and the apical surface proteins of Plasmodium falciparum. Sci Rep. 2013 3: 3178.

Gong H, Kobayashi K, Sugi T, Takemae H, Ishiwa A, Recuenco FC, Murakoshi F, Xuan X, Horimoto T, Akashi H, Kato K: Characterization and binding analysis of a microneme adhesive repeat domain-containing protein from Toxoplasma gondii. Parasitol Int. 2013 63(3):381-388.

Ozawa, M., Shimojima M, Goto H, Watanabe S, Hatta Y, Kiso M, Furuta Y, Horimoto T, Peters NR, Hoffmann MF, Kawaoka Y: A cell-based high-throughput screening system for influenza A viral RNA transcription/replication inhibitors. Sci Rep. 2013 3:1106.

Gen F, Yamada S, Kato K, Akashi H, Kawaoka Y, Horimoto T. Attenuation of an influenza A virus due to alteration of its hemagglutinin-neuraminidase functional balance in mice. Arch Virol. 2013 158(5):1003-1011.

Murakoshi F, Horimoto T, Kato K. Molecular characterization of Cryptosporidium isolates from calves in Ishikari District, Hokkaido, Japan. J Vet Med Sci. 2013 75(7):837-840.

Iwanaga T, Sugi T, Kobayashi K, Takemae H, Gong H, Ishiwa A, Murakoshi F, Recuenco FC, Horimoto T, Akashi H, Kato K. Characterization of Plasmodium falciparum cdc2-related kinase and the effects of a CDK inhibitor on the parasites in erythrocytic schizogony. Parasit International. 2013 62(5):423-430.

 

2012

Murakami S, Terasaki K, Narayanan K, Makino S. Roles of the coding and noncoding regions of Rift Valley fever virus RNA genome segments in viral RNA packaging. J Virol. 2012 86(7):4034-9.

Yamada S, Shinya K, Takada A, Ito T, Susuki T, Suzuki Y, Le QM, Ebina M, Kasai N, Kida H, Horimoto T, Rivailler P, Chen LM, Donis R, Kawaoka Y: Adaptation of a duck influenza A virus in quail. J Virol. 2012 86(3):1411-1420.

Gong H, Kobayashi K, Sugi T, Takemae H, Kurokawa H, Horimoto T, Akashi H, Kato K: A novel PAN/apple domain- containing protein from Toxoplasma gondii: characterization and receptor identification. PLoS ONE. 2012 7(1):e30169.

Kobayashi K, Takemae H, Sugi T, Gong H, Recuenco FC, Iwanaga T, Horimoto T, Akashi H, Kato K. Approach for the development of antiprotozoal agents and vaccines on the basis of invasion inhibitory effect of heparin. Jpn J Vet Parasitol. 2012 11(1): 23.

Tsuda S, Watanabe S, Masangkay JS, Mizutani T, Alviola P, Ueda N, Iha K, Taniguchi S, Fujii H, Kato K, Horimoto T, Kyuwa S, Yoshikawa Y, Akashi H. Genomic and serological detection of bat coronavirus from bats in the Philippines. Arch Virol. 2012 157(12): 2349-2355.

Katsura H, Iwatsuki-Horimoto K, Fukuyama S, Watanabe S, Sakabe S, Hatta Y, Murakami S, Shimojima M, Horimoto T, Kawaoka Y: A replication-incompetent virus possessing an uncleavable hemagglutinin as an influenza vaccine. Vaccine. 2012 30(42): 6027-6033.

Suda Y, Yamane D, Zahoor MA, Kato K, Horimoto T, Akashi H. Subcellular formation and localization of bovine viral diarrhea virus replication complex. Jpn J Vet Res. 2012 60 (suppl.): 78.

Murakami S, Horimoto T, Ito M, Takano R, Katsura H, Shimojima M, Kawaoka Y. Enhanced growth of influenza vaccine seed viruses in Vero cells mediated by broadening the optimal pH range for virus membrane fusion. J Virol. 2012 86(3):1405-10.

 

2011

Kiso M, Ozawa M, Le MQ, Imai H, Takahashi K, Kakugawa S, Noda T, Horimoto T, and Kawaoka Y. Effect of an asparagine-to-serine mutation at position 294 in neuraminidase on the pathogenicity of highly pathogenic H5N1 influenza A virus. J Virol. 2011 85(10):860-866.

Iwatsuki-Horimoto K, Horimoto T, Tamura D, Kiso M, Kawakami E, Hatakeyama S, Ebihara Y, Koibuchi T, Fujii T, Takahashi K, Shimojima M, Sakai-Tagawa Y, Ito M, Sakabe S, Iwasa A, Takahashi K, Ishii T, Gorai T, Tsuji K, Iwamoto A, and Kawaoka Y: Sero-prevalence of pandemic (H1N1) 2009 influenza A virus among schoolchildren and their parents in Tokyo, Japan. Clin Vaccine Immunol. 2011 18(5):860-866.

Akarsu H, Iwatsuki-Horimoto K, Noda T, Katsura H, Baudin F, Horimoto T, and Kawaoka Y: Structure-based design of NS2 mutants for attenuated influenza A virus vaccines. Virus Res. 2011 155(1):240-248.

Horimoto T, Maeda K, Murakami S, Iwatsuki-Horimoto K, Ito T, Suzuki K, Yokoyama M, and Kawaoka Y: Highly pathogenic avian influenza virus infection in feral raccoons, Japan. Emerg Infect Dis. 2011 17(4):714-717.

Sakabe S, Iwatsuki-Horimoto K, Takano R, Nidom CA, Le MT, Nagamura-Inoue T, Horimoto T, Yamashita N, Kawaoka Y: Cytokine production by primary human macrophages infected with highly pathogenic H5N1 or pandemic H1N1 2009 influenza viruses. J Gen Virol. 2011 92(Pt 6):1428-1434.

Terasaki K, Murakami S, Lokugamage KG, Makino S. Mechanism of tripartite RNA genome packaging in Rift Valley fever virus. Proc Natl Acad Sci U S A. 2011 108(2):804-9.

Sugi T, Kato K, Kobayashi K, Kurokawa H, Takemae H, Gong H, Recuenco FC, Iwanaga T, Horimoto T, Akashi H. 1NM-PP1 treatment of mice infected with Toxoplasma gondii. J Vet Med Sci. 2011 73(10): 1377-1379.

 

2010

Haga T, Horimoto T. Animal Models to Study Influenza Virus Pathogenesis and Control. The Open Antimicrobial Agents Journal. 2010 15-21.

Horimoto T,  Kawaoka Y. Pandemic Influenza. The Open Antimicrobial Agents Journal. 2010 9-14.

Sakabe S, Iwatsuki-Horimoto K, Horimoto T, Nidom CA, Le Mt, Takano R, Kubota-Koketsu R, Okuno Y, Ozawa M, Kawaoka Y. A cross-reactive neutralizing monoclonal antibody protects mice from H5N1 and pandemic (H1N1) 2009 virus infection. Antiviral Res. 2010 88(3):249-55.

Imai H, Shinya K, Takano R, Kiso M, Muramoto Y, Sakabe S, Murakami S, Ito M, Yamada S, Le MT, Nidom CA, Sakai-Tagawa Y, Takahashi K, Omori Y, Noda T, Shimojima M, Kakugawa S, Goto H, Iwatsuki-Horimoto K, Horimoto T, Kawaoka Y. The HA and NS genes of human H5N1 influenza A virus contribute to high virulence in ferrets. PLoS Pathog. 2010 6(9):e1001106.

Tamura D, Fujino M, Ozawa M, Iwatsuki-Horimoto K, Goto H, Sakai-Tagawa Y, Horimoto T, Nirasawa M, Kawaoka Y. Significance of seasonal influenza viruses in the stool of pediatric patients. Pediatr Infect Dis J. 2010 29(6):578-9.

 

2009

Itoh Y, Shinya K, Kiso M, Watanabe T, Sakoda Y, Hatta M, Muramoto Y, Tamura D, Sakai-Tagawa Y, Noda T, Sakabe S, Imai M, Hatta Y, Watanabe S, Li C, Yamada S, Fujii K, Murakami S, Imai H, Kakugawa S, Ito M, Takano R, Iwatsuki-Horimoto K, Shimojima M, Horimoto T, Goto H, Takahashi K, Makino A, Ishigaki H, Nakayama M, Okamatsu M, Takahashi K, Warshauer D, Shult PA, Saito R, Suzuki H, Furuta Y, Yamashita M, Mitamura K, Nakano K, Nakamura M, Brockman-Schneider R, Mitamura H, Yamazaki M, Sugaya N, Suresh M, Ozawa M, Neumann G, Gern J, Kida H, Ogasawara K, Kawaoka Y. In vitro and in vivo characterization of new swine-origin H1N1 influenza viruses. Nature. 2009 20;460(7258):1021-5.

Fujii K, Ozawa M, Iwatsuki-Horimoto K, Horimoto T, Kawaoka Y. Incorporation of influenza A virus genome segments does not absolutely require wild-type sequences. J Gen Virol. 2009  90(Pt 7):1734-40.

Tamura D, Mitamura K, Yamazaki M, Fujino M, Nirasawa M, Kimura K, Kiso M, Shimizu H, Kawakami C, Hiroi S, Takahashi K, Hata M, Minagawa H, Kimura Y, Kaneda S, Sugita S, Horimoto T, Sugaya N, Kawaoka Y. Oseltamivir-resistant influenza a viruses circulating in Japan. J Clin Microbiol. 2009 47(5):1424-7.

Ozawa M, Maeda J, Iwatsuki-Horimoto K, Watanabe S, Goto H, Horimoto T, Kawaoka Y. Nucleotide sequence requirements at the 5' end of the influenza A virus M RNA segment for efficient virus replication. J Virol. 2009 Apr;83(7):3384-8.

Kakugawa S, Shimojima M, Goto H, Horimoto T, Oshimori N, Neumann G, Yamamoto T, Kawaoka Y. Mitogen-activated protein kinase-activated kinase RSK2 plays a role in innate immune responses to influenza virus infection. J Virol. 2009 83(6):2510-7.

Makino A, Horimoto T, Kawaoka Y. Binding properties of GP1 protein of Borna disease virus. J Vet Med Sci. 2009 71(2):243-6.

Horimoto T, Kawaoka Y. Designing vaccines for pandemic influenza. Curr Top Microbiol Immunol. 2009;333:165-76. Review.

 

2008

Murakami S, Iwasa A, Iwatsuki-Horimoto K, Ito M, Kiso M, Kida H, Takada A, Nidom CA, Mai le Q, Yamada S, Imai H, Sakai-Tagawa Y, Kawaoka Y, Horimoto T. Cross-clade protective immunity of H5N1 influenza vaccines in a mouse model. Vaccine. 2008 26(50):6398-404.

Murakami S, Horimoto T, Mai le Q, Nidom CA, Chen H, Muramoto Y, Yamada S, Iwasa A, Iwatsuki-Horimoto K, Shimojima M, Iwata A, Kawaoka Y. Growth determinants for H5N1 influenza vaccine seed viruses in MDCK cells. J Virol. 2008 82(21):10502-9.

Iwatsuki-Horimoto K, Hatta Y, Hatta M, Muramoto Y, Chen H, Kawaoka Y, Horimoto T. Limited compatibility between the RNA polymerase components of influenza virus type A and B. Virus Res. 2008 135(1):161-5.

Song JH, Nguyen HH, Cuburu N, Horimoto T, Ko SY, Park SH, Czerkinsky C, Kweon MN. Sublingual vaccination with influenza virus protects mice against lethal viral infection. Proc Natl Acad Sci U S A. 2008 105(5):1644-9.

Murakami S, Horimoto T, Yamada S, Kakugawa S, Goto H, Kawaoka Y. Establishment of canine RNA polymerase I-driven reverse genetics for influenza A virus: its application for H5N1 vaccine production. J Virol. 2008 82(3):1605-9.

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東京大学農学部3号館2階209号室
（弥生キャンパス)
TEL: 03(5841)5398
E-mail: ahorimo{ATMARK}mail.ecc.u-tokyo.ac.jp
shin-murakami{ATMARK}g.ecc.u-tokyo.ac.jp

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